The current issue of Neurology reports that multiple sclerosis in children is associated with cognitive impairment and lower IQ scores more so if multiple sclerosis is diagnosed at a younger age.  There were negative impacts on school activities in 56%  of the 63 subjects. 

Reference:  Amato, M. P., Goretti, B., Ghezzi, A., Lori, S., Zipoli, V., Portaccio, E., Moiola, L., Falautano, M., De Caro, M. F., Lopez, M., Patti, F., Vecchio, R., Pozzilli, C., Bianchi, V., Roscio, M., Comi, G., Trojano, M., For the Multiple Sclerosis Study Group of the Italian Neurological Society, Cognitive and psychosocial features of childhood and juvenile MS Neurology 2008 70: 1891-1897

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