The Archives of Disease in Childhood reports that children with Prader-Willi Syndrome have a high incidence rate of scoliosis (37.5%) that increases with age. Infants and young children had approximately a 30% rate of scoliosis and adolescents had an 80% rate of scoliosis.
Reference: de Lind van Wijngaarden, Roderick F.A., de Klerk, Luuk W.L., Festen, Dederieke A.M., Hokken-Koelega, Anita C.S.
Scoliosis in Prader-Willi syndrome: Prevalence, effects of age, gender, body mass index, lean body mass and genotype
Arch Dis Child 2008 0: adc.2007.123836
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